Multi-System Inflammatory Syndrome in Kids – What You Need to Know

Inflammatory Syndrome

You may have seen news of a new inflammatory disorder in children, related to COVID-19 infection.  This new entity is called Multi system Inflammatory Disorder in Children (MIS-C for short).  The condition is still rare when looking at the entire paediatric population; however, we want to keep you aware of what to look for with this syndrome.  We are still learning more about COVID-19 every day so this blog post is based on what current information we have.

Criteria for diagnosis includes:

  • Less than 21 years of age (Age range of most cases is 1-17 with a median age of 11)
  • Fever
  • Laboratory evidence of inflammation
  • Severe illness requiring hospitalization
  • Greater than 2 organ systems involved (Cardiac, renal, respiratory, hematologic, gastrointestinal, dermatological, or neurological)
  • Current or recent Sars-Cov 2 infection: diagnosed by positive PCR nasal swab, positive antibody test, or documented interaction with a COVID-19 positive patient within the last 4 weeks.

What the syndrome looks like:

  • Fever (greater than 100.4 F) for over 24 hours
  • Abdominal pain with vomiting or diarrhea
  • Rash
  • Possible respiratory symptoms
  • Altered mental status – child seeming confused or overly sleepy

What to do if you are concerned:

  • Call your pediatrician immediately to discuss
  • Your pediatrician can determine if your child needs to be seen in the office or the ER

What to expect if you are sent to the ER for evaluation:

  • IV fluids
  • Labwork to look for signs of MIS-C, recent COVID-19 infection, and other illnesses that can present in a similar way
  • Chest X-Ray if indicated
  • ECG and Echo if indicated

Always feel comfortable calling our office with any concerns or questions 513-984-5552.  We are here to help!

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